CLINICAL RATIONALE Naltrexone hydrochloride is an opioid antagonist reported to reduce the cravings for opioids and alcohol in dependant patients; it does not diminish or prevent withdrawal symptoms. It also does not ensure abstinence from alcohol and opioids; it may, however, decrease patients motivation to.If.
Naltrexone has rarely caused serious liver disease. The risk is increased when larger doses are used. Discuss the risks and benefits with your doctor. Stop using this medication and tell your doctor right away if you develop symptoms of liver disease, including: persistent nausea/vomiting, severe.Severity: MILD.