Naltrexone adverse effects

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Naltrexone adverse effects

Posted Jun 13, 2016 by Admin

In Summary Commonly reported side effects of naltrexone include: syncope, streptococcal pharyngitis, posttraumatic stress disorder, fatigue, arthralgia, frequent headaches, panic attack, nausea, vomiting, pharyngitis, joint stiffness, nervousness, arthritis, dizziness, obsessive compulsive disorder, headache, sinus headache, anxiety, drowsiness, nasopharyngitis, sedation, tenderness at injection site, induration at. Ref Depression and suicidal ideation or attempts have occurred in all study groups receiving naltrexone for treatment of alcohol dependence. These conditions also have been reported in data collected from postmarketing experience during treatment of opioid dependence.

Ref Gastrointestinal Gastrointestinal side effects reported during treatment for alcohol dependence have included nausea (10) and vomiting (3). Gastrointestinal side effects reported in greater than 10 of patients during treatment for opioid dependence have included abdominal pain, abdominal cramps, nausea, and vomiting.

Psychiatric side effects reported during treatment of opioid dependence have included feeling down (less than 10). Depression, paranoia, hallucinations, bad dreams, and nightmares have been reported rarely. Anxiety and abnormal thinking have also been reported.

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Symptoms include tearfulness, mild nausea, abdominal cramps, restlessness, bone or joint pain, myalgia, and nasal symptoms. Ref In one study, few symptoms were reported following the first week. However, stomach cramps, inability to sleep, and frightening thoughts were reported by 30 or more of subjects.

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some.

The effects of an opiate may be attenuated during self-administration of small doses of an opioid drug. Patients taking naltrexone may not benefit from opioid-containing medications, such as cough and cold preparations, antidiarrheal preparations, and opioid analgesics.

Loss of appetite, diarrhea, constipation, and increased thirst have been reported in less than 10 of patients. Hemorrhoids, ulcer, diarrhea, excessive gas, increased appetite, and dry mouth have been reported rarely.