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    Consider the use of alternative non-opioid analgesics in these patients if possible. Hypotensive Effect EMBEDA may cause severe hypotension including orthostatic hypotension and syncope in ambulatory patients. There is an increased risk in patients whose ability to maintain blood pressure has already been compromised by.Interaction.

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Hepatitis c naltrexone

Posted Apr 21, 2016 by Admin

In all controlled and uncontrolled trials during the premarketing development of VIVITROL, more than 1100 patients with alcohol and/or opioid dependence have been treated with VIVITROL. Approximately 700 patients have been treated for 6 months or more, and more than 400 for 1 year or. Aug 12, 2013. Vivitrol (naltrexone for extended-release) injectable suspension Drug. including pre-existing alcoholic liver disease, hepatitis B and/or C.

CONCLUSIONS : XR-NTX can be used safely in eligible patients with opioid dependence, including those with underlying mild to moderate chronic HCV and/or HIV infections.

J Stud Alcohol Drugs. 2012 Nov;73(6 991-7. Hepatic safety of injectable extended-release naltrexone in patients with chronic hepatitis C and HIV infection).

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OBJECTIVE : Naltrexone (Revia, Vivitrol) is recognized as having the potential for hepatotoxicity. We evaluated the safety of intramuscular extended-release naltrexone (XR-NTX) in a cohort of patients with a high prevalence of chronic hepatitis C virus (HC V) and HIV infection undergoing treatment for opioid.

In the placebo group, 1 of patients withdrew due to injection site reactions, and

Liver chemistry tests for aspartate aminotransferase (AST alanine aminotransferase (ALT total bilirubin, gamma-glutamyl aminotransferase (GGT alkaline phosphatase, serum albumin, and total protein were obtained at the screening visit, at baseline, and monthly for up to 6 months.

Clinical Studies Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.